The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stem/progenitors

INTRODUCTION: Dysregulation of the insulin-like growth factor-1 receptor (IGF-1R)/phosphatidylinositol-3-kinase (PI3K)/Akt pathway was shown to correlate with breast cancer disease progression. Cancer stem cells are a subpopulation within cancer cells that participate in tumor initiation, radio/chem...

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Hlavní autoři: Chang, Wen-Wei, Lin, Ruey-Jen, Yu, John, Chang, Wen-Ying, Fu, Chiung-Hui, Lai, Alan Chuan-Ying, Yu, Jyh-Cherng, Yu, Alice L
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706809/
https://ncbi.nlm.nih.gov/pubmed/23663564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3423
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