Neuroprotective effects of D-Ala(2)GIP on Alzheimer's disease biomarkers in an APP/PS1 mouse model

INTRODUCTION: Type 2 diabetes mellitus has been identified as a risk factor for Alzheimer's disease (AD). An impairment of insulin signaling as well as a desensitization of its receptor has been found in AD brains. Glucose-dependent insulinotropic polypeptide (GIP) normalises insulin signaling...

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Main Authors: Faivre, Emilie, Hölscher, Christian
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706793/
https://ncbi.nlm.nih.gov/pubmed/23601582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt174
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