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Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease

INTRODUCTION: Despite the extensive mechanistic and pathological characterization of the amyloid precursor protein (APP)/presenilin-1 (PS-1) knock-in mouse model of Alzheimer's disease (AD), very little is known about the AD-relevant behavioral deficits in this model. Characterization of the ba...

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Bibliografske podrobnosti
Main Authors: Webster, Scott J, Bachstetter, Adam D, Van Eldik, Linda J
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706792/
https://ncbi.nlm.nih.gov/pubmed/23705774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt182
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