Plum, an immunoglobulin superfamily protein, regulates axon pruning by facilitating TGF-β signaling

Axon pruning during development is essential for the proper wiring of the mature nervous system, but its regulation remains poorly understood. We have identified an immunoglobulin superfamily (IgSF) transmembrane protein, Plum, that is cell-autonomously required for axon pruning of mushroom body (MB...

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Bibliografiske detaljer
Main Authors: Yu, Xiaomeng M., Gutman, Itai, Mosca, Timothy J., Iram, Tal, Özkan, Engin, Garcia, K. Christopher, Luo, Liqun, Schuldiner, Oren
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706783/
https://ncbi.nlm.nih.gov/pubmed/23664613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.03.004
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