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Prostacyclin Reversal of Lethal Endotoxemia in Dogs

Severe endotoxemia, a condition where microembolization and intravascular coagulation are thought to play important roles, was treated experimentally with prostacyclin (PGI(2)). In a study of 24 dogs, 8 control animals injected with 1.75 mg·kg(−1) of endotoxin died within 24 h. Six animals given int...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Krausz, Michael M., Utsunomiya, Takayoshi, Feuerstein, Giora, Wolfe, John H. N., Shepro, David, Hechtman, Herbert B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1981
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370672/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7009654/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110125
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