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Ligand Binding Site Identification by Higher Dimension Molecular Dynamics

We propose a new molecular dynamics (MD) protocol to identify the binding site of a guest within a host. The method utilizes a four spatial (4D) dimension representation of the ligand allowing for rapid and efficient sampling within the receptor. We applied the method to two different model receptor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yatawara, Achani K., Hodoscek, Milan, Mierke, Dale F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706581/
https://ncbi.nlm.nih.gov/pubmed/23394112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci300561b
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