Short-term treatment with tolfenamic acid improves cognitive functions in AD mice

Tolfenamic acid lowers the levels of the amyloid precursor protein (APP) and amyloid beta (Aβ) when administered to C57BL/6 mice by lowering their transcriptional regulator specificity protein 1 (SP1). To determine whether changes upstream in the amyloidogenic pathway that forms Aβ plaques would imp...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Subaiea, Gehad M., Adwan, Lina I., Ahmed, Aseef H., Stevens, Karen E., Zawia, Nasser H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706573/
https://ncbi.nlm.nih.gov/pubmed/23639209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.04.002
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