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Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation

Microglia, the resident immune cell of the central nervous system (CNS), are thought to contribute to the pathogenesis of age-related neurodegenerative disorders. It has been hypothesized that microglia undergo age-related changes in gene expression patterns that give rise to pathogenic phenotypes....

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Autors principals: Ma, Wenxin, Cojocaru, Radu, Gotoh, Norimoto, Gieser, Linn, Villasmil, Rafael, Cogliati, Tiziana, Swaroop, Anand, Wong, Wai T.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706521/
https://ncbi.nlm.nih.gov/pubmed/23608111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.03.022
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