Fgf21 Impairs Adipocyte Insulin Sensitivity in Mice Fed a Low-Carbohydrate, High-Fat Ketogenic Diet

BACKGROUND: A low-carbohydrate, high-fat ketogenic diet (KD) induces hepatic ketogenesis and is believed to affect energy metabolism in mice. As hepatic Fgf21 expression was markedly induced in mice fed KD, we examined the effects of KD feeding on metabolism and the roles of Fgf21 in metabolism in m...

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Detaylı Bibliyografya
Asıl Yazarlar: Murata, Yusuke, Nishio, Kyoji, Mochiyama, Takayuki, Konishi, Morichika, Shimada, Masaya, Ohta, Hiroya, Itoh, Nobuyuki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706421/
https://ncbi.nlm.nih.gov/pubmed/23874946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069330
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