Excessive Cytokine Response to Rapid Proliferation of Highly Pathogenic Avian Influenza Viruses Leads to Fatal Systemic Capillary Leakage in Chickens

Highly pathogenic avian influenza viruses (HPAIVs) cause lethal infection in chickens. Severe cases of HPAIV infections have been also reported in mammals, including humans. In both mammals and birds, the relationship between host cytokine response to the infection with HPAIVs and lethal outcome has...

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Bibliographic Details
Main Authors: Kuribayashi, Saya, Sakoda, Yoshihiro, Kawasaki, Takeshi, Tanaka, Tomohisa, Yamamoto, Naoki, Okamatsu, Masatoshi, Isoda, Norikazu, Tsuda, Yoshimi, Sunden, Yuji, Umemura, Takashi, Nakajima, Noriko, Hasegawa, Hideki, Kida, Hiroshi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706397/
https://ncbi.nlm.nih.gov/pubmed/23874602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068375
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