Excessive Cytokine Response to Rapid Proliferation of Highly Pathogenic Avian Influenza Viruses Leads to Fatal Systemic Capillary Leakage in Chickens

Highly pathogenic avian influenza viruses (HPAIVs) cause lethal infection in chickens. Severe cases of HPAIV infections have been also reported in mammals, including humans. In both mammals and birds, the relationship between host cytokine response to the infection with HPAIVs and lethal outcome has...

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Main Authors: Kuribayashi, Saya, Sakoda, Yoshihiro, Kawasaki, Takeshi, Tanaka, Tomohisa, Yamamoto, Naoki, Okamatsu, Masatoshi, Isoda, Norikazu, Tsuda, Yoshimi, Sunden, Yuji, Umemura, Takashi, Nakajima, Noriko, Hasegawa, Hideki, Kida, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706397/
https://ncbi.nlm.nih.gov/pubmed/23874602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068375
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