High prevalence of mutation in the Plasmodium falciparum dhfr and dhps genes in field isolates from Sabah, Northern Borneo

BACKGROUND: Sulphadoxine-pyrimethamine (SP) has been in use for the treatment of uncomplicated falciparum malaria in Malaysia since the 1970s and is still widely employed in spite of widespread clinical resistance. Resistance to SP is known to be mediated by mutations in the pfdhfr and pfdhps genes....

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Bibliografiset tiedot
Päätekijät: Abdullah, Noor Rain, Norahmad, Nor Azrina, Jelip, Jenarun, Sulaiman, Lokman Hakim, Mohd Sidek, Hasidah, Ismail, Zakiah, Noedl, Harald
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2013
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706343/
https://ncbi.nlm.nih.gov/pubmed/23758930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-198
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