Activation of renin-angiotensin system is involved in dyslipidemia-mediated renal injuries in apolipoprotein E knockout mice and HK-2 cells

BACKGROUND: Dyslipidemia and activation of renin-angiotensin system (RAS) contribute to the progression of chronic kidney disease (CKD). This study investigated possible synergistic effects of intrarenal RAS activation with hyperlipidemia in renal injuries. METHODS: Apolipoprotein knockout mice were...

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Detalhes bibliográficos
Main Authors: Ni, Jie, Ma, Kun-Ling, Wang, Chang-Xian, Liu, Jing, Zhang, Yang, Lv, Lin-Li, Ni, Hai-Feng, Chen, Ya-Xi, Ruan, Xiong-Zhong, Liu, Bi-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706287/
https://ncbi.nlm.nih.gov/pubmed/23570453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-12-49
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