A Randomized Double-Blind, Placebo-Controlled Trial of Minocycline in Children and Adolescents with Fragile X Syndrome

OBJECTIVE: Minocycline rescued synaptic abnormalities and improved behavior in the fragile X mouse model. Prior open-label human studies demonstrated benefits in individuals with fragile X syndrome (FXS); however, its efficacy in patients with FXS has not been assessed in a controlled trial. METHOD:...

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Main Authors: Leigh, Mary Jacena S., Nguyen, Danh V., Mu, Yi, Winarni, Tri I., Schneider, Andrea, Chechi, Tasleem, Polussa, Jonathan, Doucet, Paul, Tassone, Flora, Rivera, Susan M., Hessl, David, Hagerman, Randi J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706260/
https://ncbi.nlm.nih.gov/pubmed/23572165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/DBP.0b013e318287cd17
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