Bcr-Abl tyrosine kinase inhibitors- current status

Bcr-Abl plays a central role in the development of chromosome positive leukaemia. Chronic Myeloid leukaemia occurs due to increase proliferation and resistance to apoptosis by Bcr-Abl positive cells. Imatinib (STI571) is the first drug in the family of Bcr-Abl tyrosine kinase inhibitors while Niloti...

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Bibliografiske detaljer
Main Authors: Mughal, Anum, Aslam, Hafiz Muhammad, Khan, Aga Muhammad Hammad, Saleem, Shafaq, Umah, Ribak, Saleem, Maria
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Letter to the Editor
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706229/
https://ncbi.nlm.nih.gov/pubmed/23787070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-9378-8-23
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