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Effect of Pulse Frequency on the Osteogenic Differentiation of Mesenchymal Stem Cells in a Pulsatile Perfusion Bioreactor

Perfusion bioreactors are a promising in vitro strategy to engineer bone tissue because they supply needed oxygen and nutrients and apply an osteoinductive mechanical stimulus to osteoblasts within large porous three-dimensional scaffolds. Model two-dimensional studies have shown that dynamic flow c...

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Bibliografiske detaljer
Main Authors: Kavlock, Katherine D., Goldstein, Aaron S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Mechanical Engineers 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705976/
https://ncbi.nlm.nih.gov/pubmed/22010740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1115/1.4004919
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