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Loss of RASSF1A Expression in Colorectal Cancer and Its Association with K-ras Status

Background. The RAS-association domain family 1 A (RASSF1A) is a classical member of RAS effectors regulating cell proliferation and apoptosis. Loss of RASSF1A expression may shift the balance towards a growth-promoting effect without the necessity of activating K-ras mutations. Its potential associ...

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Detalhes bibliográficos
Main Authors: Cao, Dan, Chen, Ye, Tang, Yuan, Peng, Xing-Chen, Dong, Hang, Li, Long-Hao, Cheng, Ke, Ge, Jun, Liu, Ji-Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705944/
https://ncbi.nlm.nih.gov/pubmed/23865079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/976765
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