Bradykinin Production and Increased Pulmonary Endothelial Permeability during Acute Respiratory Failure in Unanesthetized Sheep

To investigate mechanisms of pulmonary edema in respiratory failure, we studied unanesthetized sheep with vascular catheters, pleural balloons, and chronic lung lymph fistulas. Animals breathed either a hypercapnic-enriched oxygen (n = 5) or a hypercapnic-hypoxic (n = 5) gas mixture for 2 h. Every 1...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	O'Brodovich, Hugh M., Stalcup, S. Alex, Pang, Leila Mei, Lipset, Joel S., Mellins, Robert B.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1981
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7007439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110061
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