Levetiracetam versus phenytoin for seizure prophylaxis in severe traumatic brain injury

OBJECT: Current standard of care for patients with severe traumatic brain injury (TBI) is prophylactic treatment with phenytoin for 7 days to decrease the risk of early posttraumatic seizures. Phenytoin alters drug metabolism, induces fever, and requires therapeutic-level monitoring. Alternatively,...

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Autori principali: Jones, Kristen E., Puccio, Ava M., Harshman, Kathy J., Falcione, Bonnie, Benedict, Neal, Jankowitz, Brian T., Stippler, Martina, Fischer, Michael, Sauber-Schatz, Erin K., Fabio, Anthony, Darby, Joseph M., Okonkwo, David O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705765/
https://ncbi.nlm.nih.gov/pubmed/18828701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/FOC.2008.25.10.E3
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