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Lactoferrin enhances hydroxyl radical production by human neutrophils, neutrophil particulate fractions, and an enzymatic generating system.

During phagocytosis, neutrophils take oxygen from the surrounding medium and convert it to superoxide anion (O2-) and hydrogen peroxide (H2O2). Hydroxyl radical (.OH), a particularly potent oxidant, is believed to be produced by interaction between O2- and H2O2 in the presence of iron, according to...

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Udgivet i:J Clin Invest
Principais autores: Ambruso, D R, Johnston, R B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370575/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6780607/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110042
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