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In-silico analysis of caspase-3 and -7 proteases from blood-parasitic Schistosoma species (Trematoda) and their human host

Proteolytic enzymes of the caspase family, which reside as latent precursors in most nucleated metazoan cells, are core effectors of apoptosis. Of them, the executioner caspases- 3 and -7 exist within the cytosol as inactive dimers and are activated by a process called dimerization. Caspase inhibiti...

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Detalhes bibliográficos
Main Authors: Kumar, Shakti, Biswal, Devendra Kumar, Tandon, Veena
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705615/
https://ncbi.nlm.nih.gov/pubmed/23847399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630009456
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