ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21(WAF1)

ZNF313 encoding a zinc-binding protein is located at chromosome 20q13.13, which exhibits a frequent genomic amplification in multiple human cancers. However, the biological function of ZNF313 remains largely undefined. Here we report that ZNF313 is an ubiquitin E3 ligase that has a critical role in...

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Detalhes bibliográficos
Main Authors: Han, J, Kim, Y-L, Lee, K-W, Her, N-G, Ha, T-K, Yoon, S, Jeong, S-I, Lee, J-H, Kang, M-J, Lee, M-G, Ryu, B-K, Baik, J-H, Chi, S-G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705597/
https://ncbi.nlm.nih.gov/pubmed/23645206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.33
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