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Effects of pulling forces, osmotic pressure, condensing agents, and viscosity on the thermodynamics and kinetics of DNA ejection from bacteriophages to bacterial cells: a computational study

In the current work, we report on simulations of double-stranded DNA (dsDNA) ejection from bacteriophage φ29 into a bacterial cell. The ejection was studied with a coarse-grained model, in which viral dsDNA was represented by beads on a torsionless string. The bacteriophage’s capsid and the bacteria...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Petrov, Anton S., Douglas, Scott S., Harvey, Stephen C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705564/
https://ncbi.nlm.nih.gov/pubmed/23399864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0953-8984/25/11/115101
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