Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1-antitrypsin-deficient individuals.

To evaluate the contribution of mononuclear phagocytes, and particularly alveolar macrophages, to alpha-1-antitrypsin (alpha 1AT) production in normal and alpha 1AT-deficient individuals, Northern analysis with a human alpha 1AT complementary DNA was used to demonstrate that alpha 1AT messenger RNA...

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Pubblicato in:	J Clin Invest
Autori principali:	Mornex, J F, Chytil-Weir, A, Martinet, Y, Courtney, M, LeCocq, J P, Crystal, R G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370556/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3486887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112524
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