Recruitment of Transcription Complexes to the β-Globin Gene Locus in Vivo and in Vitro

Erythroid-specific, high level expression of the β-globin genes is regulated by the locus control region (LCR), composed of multiple DNase I-hypersensitive sites and located far upstream of the genes. Recent studies have shown that LCR core elements recruit RNA polymerase II (pol II). In the present...

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Main Authors: Vieira, Karen F., Levings, Padraic P., Hill, Meredith A., Crusselle, Valerie J., Kang, Sung-Hae Lee, Engel, James Douglas, Bungert, Jörg
格式: Artigo
語言:Inglês
出版: 2004
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705557/
https://ncbi.nlm.nih.gov/pubmed/15385559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M408883200
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