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Brain mitochondrial metabolic dysfunction and glutamate level reduction in the pilocarpine model of temporal lobe epilepsy in mice

Although certain metabolic characteristics such as interictal glucose hypometabolism are well established for temporal lobe epilepsy (TLE), its pathogenesis still remains unclear. Here, we performed a comprehensive study of brain metabolism in a mouse model of TLE, induced by pilocarpine–status epil...

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Detalhes bibliográficos
Main Authors: Smeland, Olav B, Hadera, Mussie G, McDonald, Tanya S, Sonnewald, Ursula, Borges, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705438/
https://ncbi.nlm.nih.gov/pubmed/23611869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.54
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