Cross-reactivity of human and murine anti-DNA antibodies with heparan sulfate. The major glycosaminoglycan in glomerular basement membranes.

In 30 of 33 human systemic lupus erythematosus (SLE) sera and in 10 sera from MRL/l mice with spontaneous SLE, antibodies against heparan sulfate were detected. The anti-heparan sulfate titers showed a significant correlation with the anti-DNA antibody titers. By inhibition studies it was demonstrat...

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Pubblicato in:	J Clin Invest
Autori principali:	Faaber, P, Rijke, T P, van de Putte, L B, Capel, P J, Berden, J H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370540/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2940265/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112508
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