Defective suppression by insulin of leucine-carbon appearance and oxidation in type 1, insulin-dependent diabetes mellitus. Evidence for insulin resistance involving glucose and amino acid metabolism.

To determine whether a resistance to insulin in type 1, insulin-dependent diabetes mellitus (IDDM) is extended to both glucose and amino acid metabolism, six normal subjects and five patients with IDDM, maintained in euglycemia with intravenous insulin administration, were infused with L-[4,5-3H]leu...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Tessari, P, Nosadini, R, Trevisan, R, De Kreutzenberg, S V, Inchiostro, S, Duner, E, Biolo, G, Marescotti, M C, Tiengo, A, Crepaldi, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3519679/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112504
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