UV-Induced Nuclear Import of XPA Is Mediated by Importin-α4 in An ATR-Dependent Manner

Xeroderma pigmentosum Group A (XPA) is a crucial factor in mammalian nucleotide excision repair (NER) and nuclear import of XPA from the cytoplasm for NER is regulated in cellular DNA damage responses in S-phase. In this study, experiments were carried out to determine the transport mechanisms that...

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Main Authors: Li, Zhengke, Musich, Phillip R., Cartwright, Brian M., Wang, Hui, Zou, Yue
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704644/
https://ncbi.nlm.nih.gov/pubmed/23861882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068297
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