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Probabilistic models for CRISPR spacer content evolution

BACKGROUND: The CRISPR/Cas system is known to act as an adaptive and heritable immune system in Eubacteria and Archaea. Immunity is encoded in an array of spacer sequences. Each spacer can provide specific immunity to invasive elements that carry the same or a similar sequence. Even in closely relat...

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Autori principali: Kupczok, Anne, Bollback, Jonathan P
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704272/
https://ncbi.nlm.nih.gov/pubmed/23442002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-54
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