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Probabilistic models for CRISPR spacer content evolution

BACKGROUND: The CRISPR/Cas system is known to act as an adaptive and heritable immune system in Eubacteria and Archaea. Immunity is encoded in an array of spacer sequences. Each spacer can provide specific immunity to invasive elements that carry the same or a similar sequence. Even in closely relat...

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Detalhes bibliográficos
Main Authors: Kupczok, Anne, Bollback, Jonathan P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704272/
https://ncbi.nlm.nih.gov/pubmed/23442002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-54
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