Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man.

The consequences of inhibiting the metabolism of prostaglandin G2 to thromboxane A2 in man were studied by using an inhibitor of thromboxane synthase, 4-[2-(IH-imidazol-1-yl)ethoxy] benzoic acid hydrochloride (dazoxiben). Single doses of 25, 50, 100, and 200 mg of dazoxiben were administered to heal...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	FitzGerald, G A, Brash, A R, Oates, J A, Pedersen, A K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1983
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6355181/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111089
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