Chlorpropamide action on renal concentrating mechanism in rats with hypothalamic diabetes insipidus.

To determine vasopressin (VP)-potentiating effect of chlorpropamide (CPMD), we studied the effect of CPMD in vivo and in vitro in kidneys and in specific tubule segments of rats with hypothalamic diabetes insipidus, homozygotes of the Brattleboro strain (DI rats). Rats on ad lib. water intake were t...

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Pubblicato in:	J Clin Invest
Autori principali:	Kusano, E, Braun-Werness, J L, Vick, D J, Keller, M J, Dousa, T P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1983
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370414/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6313759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111086
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