Ru(CO)(3)Cl(Glycinate) (CORM-3): A Carbon Monoxide–Releasing Molecule with Broad-Spectrum Antimicrobial and Photosensitive Activities Against Respiration and Cation Transport in Escherichia coli

Aims: Carbon monoxide (CO) delivered to cells and tissues by CO-releasing molecules (CO-RMs) has beneficial and toxic effects not mimicked by CO gas. The metal carbonyl Ru(CO)(3)Cl(glycinate) (CORM-3) is a novel, potent antimicrobial agent. Here, we established its mode of action. Results: CORM-3 in...

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Detalhes bibliográficos
Main Authors: Wilson, Jayne Louise, Jesse, Helen E., Hughes, Bethan, Lund, Victoria, Naylor, Kathryn, Davidge, Kelly S., Cook, Gregory M., Mann, Brian E., Poole, Robert K.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704104/
https://ncbi.nlm.nih.gov/pubmed/23186316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4784
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