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Formation of diiodotyrosine from thyroxine. Ether-link cleavage, an alternate pathway of thyroxine metabolism.

Studies were performed to elucidate the nature of the pathway of hepatic thyroxine (T4) metabolism that is activated by inhibitors of liver catalase. For this purpose, the metabolism of T4 in homogenates of rat liver was monitored with T4 labeled with 125I either at the 5'-position of the outer-ring...

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Pubblicato in:J Clin Invest
Autori principali: Balsam, A, Sexton, F, Borges, M, Ingbar, S H
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370407/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6630509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111079
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