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Fitness landscape for nucleosome positioning

Histone–DNA complexes, so-called nucleosomes, are the building blocks of DNA packaging in eukaryotic cells. The histone-binding affinity of a local DNA segment depends on its elastic properties and determines its accessibility within the nucleus, which plays an important role in the regulation of ge...

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Detalhes bibliográficos
Main Authors: Weghorn, Donate, Lässig, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704022/
https://ncbi.nlm.nih.gov/pubmed/23784778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210887110
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