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Genetic reconstitution of tumorigenesis in primary intestinal cells
Animal models for human colorectal cancer recapitulate multistep carcinogenesis that is typically initiated by activation of the Wnt pathway. Although potential roles of both genetic and environmental modifiers have been extensively investigated in vivo, it remains elusive whether epithelial cells d...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703980/ https://ncbi.nlm.nih.gov/pubmed/23776211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221926110 |
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