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Genetic reconstitution of tumorigenesis in primary intestinal cells

Animal models for human colorectal cancer recapitulate multistep carcinogenesis that is typically initiated by activation of the Wnt pathway. Although potential roles of both genetic and environmental modifiers have been extensively investigated in vivo, it remains elusive whether epithelial cells d...

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Detalhes bibliográficos
Main Authors: Onuma, Kunishige, Ochiai, Masako, Orihashi, Kaoru, Takahashi, Mami, Imai, Toshio, Nakagama, Hitoshi, Hippo, Yoshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703980/
https://ncbi.nlm.nih.gov/pubmed/23776211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221926110
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