IKK epsilon kinase is crucial for viral G protein-coupled receptor tumorigenesis

G protein-coupled receptors (GPCRs) are seven-transmembrane proteins that transmit diverse extracellular signals across a membrane. Herpesvirus genomes encode multiple GPCRs implicated in viral pathogenesis. Kaposi sarcoma-associated herpesvirus GPCR (kGPCR) activates proliferative pathways and, whe...

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Bibliografski detalji
Glavni autori: Wang, Yi, Lu, Xiaolu, Zhu, Lining, Shen, Yan, Chengedza, Shylet, Feng, Hao, Wang, Laiyee, Jung, Jae U., Gutkind, J. Silvio, Feng, Pinghui
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703966/
https://ncbi.nlm.nih.gov/pubmed/23771900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219829110
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