Dual Silencing of Hsp27 and c-FLIP Enhances Doxazosin-Induced Apoptosis in PC-3 Prostate Cancer Cells

We evaluated effect of dual gene silencing of Hsp27 and c-FLIP in doxazosin-induced apoptosis of PC-3 cell. After transfection using Hsp27 and c-FLIP siRNA mixture (dual silencing), doxazosin treatment was done at the concentrations of 1, 10, and 25 μM. We checked apoptosis of PC-3 cells with and TU...

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Main Authors: Kim, Sang Soo, Cho, Hee-Ju, Cho, Jeong-Man, Kang, Jung Yoon, Yang, Hyun-Won, Yoo, Tag Keun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703906/
https://ncbi.nlm.nih.gov/pubmed/23853530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/174392
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