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Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells.

Purified human lung mast cells released histamine, leukotrienes, prostaglandin (PG) D2, thromboxane B2 (TxB2), and PGF2 alpha in response to anti-IgE stimulation. Incubation of the cells for 24 h with 10(-6) M dexamethasone, a treatment that inhibits mediator release from human basophils, had no eff...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Schleimer, R P, Schulman, E S, MacGlashan, D W, Peters, S P, Hayes, E C, Adams, G K, Lichtenstein, L M, Adkinson, N F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370388/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6134755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110938
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