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Macrophage-Derived Matrix Vesicles: An Alternative Novel Mechanism for Microcalcification in Atherosclerotic Plaques

RATIONALE: We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease (CRD) and mineral imbalance accelerates calcification and the subsequent release of matrix vesicles (MVs) — precursors of microcalcification. OBJECTIVE:...

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Detalhes bibliográficos
Main Authors: New, Sophie E., Goettsch, Claudia, Aikawa, Masanori, Marchini, Julio F., Shibasaki, Manabu, Yabusaki, Katsumi, Libby, Peter, Shanahan, Catherine M., Croce, Kevin, Aikawa, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703850/
https://ncbi.nlm.nih.gov/pubmed/23616621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301036
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