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HLA identical leukemia cells and T cell growth factor activate cytotoxic T cell recognition of minor locus histocompatibility antigens in vitro.

Lymphocytes from a healthy HLA-identical bone marrow transplant donor were tested for their ability to destroy her brother's acute myelogenous leukemia blasts in vitro. Primary mixed lymphocyte culture (MLC) and cell-mediated lysis (CML) responses between the patient's remission (pretransplant) and...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Sondel, P M, Hank, J A, Wendel, T, Flynn, B, Bozdech, M J
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370383/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6223050/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110933
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