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Immune-mediated β-cell death in type 1 diabetes: lessons from human β-cell lines

Type 1 diabetes (T1D) is a chronic, multifactorial disorder that results from a contretemps of genetic and environmental factors. Autoimmune attack and functional inhibition of the insulin-producing β cells in the pancreas lead to the inability of β cells to metabolize glucose, and thus results the...

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Detalhes bibliográficos
Main Authors: Lightfoot, Yaíma L., Chen, Jing, Mathews, Clayton E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703770/
https://ncbi.nlm.nih.gov/pubmed/22924552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2362.2012.02711.x
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