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Discovery of Widespread GTP-Binding Motifs in Genomic DNA and RNA

Biological RNAs that bind small-molecules have been implicated in a variety of regulatory and catalytic processes. Inspired by these examples, we used in vitro selection to search a pool of genomeencoded RNA fragments for naturally occurring GTP aptamers. Several classes of aptamers were identified,...

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Bibliographic Details
Main Authors: Curtis, Edward A., Liu, David R.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703636/
https://ncbi.nlm.nih.gov/pubmed/23601641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.02.015
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