Anti–IL-17A Treatment Reduces Clinical Score and VCAM-1 Expression Detected by in Vivo Magnetic Resonance Imaging in Chronic Relapsing EAE ABH Mice

IL-17 is argued to play an important role in the multiple sclerosis–like disease experimental autoimmune encephalitis (EAE). We investigated the therapeutic effects of anti–IL-17A in a chronic relapsing EAE ABH mouse model using conventional scoring, quantitative behavioral outcomes, and a novel vas...

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Autors principals: Mardiguian, Silvy, Serres, Sébastien, Ladds, Emma, Campbell, Sandra J., Wilainam, Panop, McFadyen, Charles, McAteer, Martina, Choudhury, Robin P., Smith, Paul, Saunders, Fay, Watt, Gillian, Sibson, Nicola R., Anthony, Daniel C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2013
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703548/
https://ncbi.nlm.nih.gov/pubmed/23602647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.02.029
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