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Systematic simulation of cross-reactivity predicts ambiguity in Tk memory: It may save lives of the infected, but limits specificities vital for further responses
The present study uses the agent-based model IMMSIM to simulate immune responses to a viral infection, with a focus on the impact of preformed memory (homologous and heterologous) on the quality and the efficacy of the response. The in machina results confirm the observed thwarting of new, naïve res...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703517/ https://ncbi.nlm.nih.gov/pubmed/21231890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2011.523275 |
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