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The “window of susceptibility” for inflammation in the immature central nervous system is characterized by a leaky blood brain barrier and the local expression of inflammatory chemokines

Early in postnatal development, the immature central nervous system (CNS) is more susceptible to inflammation than its adult counterpart. We show here that this “window of susceptibility” is characterized by the presence of leaky vessels in the CNS, and by a global chemokine expression profile which...

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Main Authors: Schoderboeck, Lucia, Adzemovic, Milena, Nicolussi, Eva-Maria, Crupinschi, Claudia, Hochmeister, Sonja, Fischer, Marie-Therese, Lassmann, Hans, Bradl, Monika
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703512/
https://ncbi.nlm.nih.gov/pubmed/19520164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.05.026
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