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SC erythrocytes have an abnormally high intracellular hemoglobin concentration. Pathophysiological consequences.

We have examined 20 SC patients on Percoll-Stractan continuous density gradients and find that they have an elevated mean corpuscular hemoglobin concentration (MCHC). Reduction of the MCHC to normal values results in amelioration of four physiologically important blood abnormalities: decreased oxyge...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fabry, M E, Kaul, D K, Raventos-Suarez, C, Chang, H, Nagel, R L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1982
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC370350/
https://ncbi.nlm.nih.gov/pubmed/7174796
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