Synergistic activation by collagen and 15-hydroxy-9 alpha,11 alpha-peroxidoprosta-5,13-dienoic acid (PGH2) of phosphatidylinositol metabolism and arachidonic acid release in human platelets.

Collagen stimulates the activation of phosphatidylinositol (PI)-specific phospholipase C (EC 3.1.4.10) in human platelets, as manifested by the disappearance of PI, the transient formation of diacylglycerol (DG), and release of myoinositol. Platelets exposed to collagen also form lysophosphatidylino...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Rittenhouse, S E, Allen, C L
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1982
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370338/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6816811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110720
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