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Genetic Variability in Markers of HLA-C Expression in Two Diverse South African Populations

An insertion-deletion (indel) polymorphism within the 3′ untranslated region (UTR) of HLA-C has been shown to be involved in the regulation of HLA-C expression. Individuals who carry a deletion at this position exhibit increased HLA-C expression, which associates with lower viral set point in HIV-1...

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Detalhes bibliográficos
Main Authors: Gentle, Nikki L., Paximadis, Maria, Puren, Adrian, Tiemessen, Caroline T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702582/
https://ncbi.nlm.nih.gov/pubmed/23861805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067780
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