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Quantification of Errors in Ordinal Outcome Scales Using Shannon Entropy: Effect on Sample Size Calculations

OBJECTIVE: Clinical trial outcomes often involve an ordinal scale of subjective functional assessments but the optimal way to quantify results is not clear. In stroke, the most commonly used scale, the modified Rankin Score (mRS), a range of scores (“Shift”) is proposed as superior to dichotomizatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mandava, Pitchaiah, Krumpelman, Chase S., Shah, Jharna N., White, Donna L., Kent, Thomas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702531/
https://ncbi.nlm.nih.gov/pubmed/23861800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067754
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