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Preliminary crystallographic analysis of the N-terminal PDZ-like domain of periaxin, an abundant peripheral nerve protein linked to human neuropathies

Periaxin (PRX) is an abundant protein in peripheral nerves and contains a predicted PDZ-like domain at its N-terminus. The large isoform, L-PRX, is required for the maintenance of myelin in the peripheral nervous system and its defects cause neurological disease. Here, the human periaxin PDZ-like do...

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Bibliografiske detaljer
Main Authors: Han, Huijong, Kursula, Petri
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702330/
https://ncbi.nlm.nih.gov/pubmed/23832213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113016266
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